Tools (5)

search_trials
get_trial
get_trials_by_condition
get_trials_by_sponsor
report_feedback

search_trials

Search ClinicalTrials.gov for clinical trials with flexible filters.

Covers 500K+ registered clinical trials worldwide. Returns trial summaries
including NCT ID, title, status, phase, conditions, interventions, and sponsor.

Args:
query: General search term (searches all fields). Examples: "aspirin heart",
"mRNA vaccine", "CRISPR gene therapy".
condition: Filter by condition or disease. Examples: "diabetes",
"breast cancer", "Alzheimer's disease", "COVID-19".
intervention: Filter by intervention/treatment. Examples: "pembrolizumab",
"cognitive behavioral therapy", "radiation".
status: Filter by trial status. One of: RECRUITING, NOT_YET_RECRUITING,
ACTIVE_NOT_RECRUITING, COMPLETED, TERMINATED, WITHDRAWN, SUSPENDED,
ENROLLING_BY_INVITATION, UNKNOWN.
phase: Filter by trial phase. One of: EARLY_PHASE1, PHASE1, PHASE2,
PHASE3, PHASE4, NA.
sponsor: Filter by sponsor organization. Examples: "Pfizer", "NIH",
"Mayo Clinic".
max_results: Number of results to return (1-50, default 10).

Returns:
List of trial summaries with nct_id, brief_title, overall_status, phase,
conditions, interventions, sponsor, start_date, enrollment.

Parameter	Type	Required	Description
`query`	`any`	optional	General search term (searches all fields). Examples: "aspirin heart", "mRNA vaccine", "CRISPR gene therapy".
`condition`	`any`	optional	Filter by condition or disease. Examples: "diabetes", "breast cancer", "Alzheimer's disease", "COVID-19".
`intervention`	`any`	optional	Filter by intervention/treatment. Examples: "pembrolizumab", "cognitive behavioral therapy", "radiation".
`status`	`any`	optional	Filter by trial status. One of: RECRUITING, NOT_YET_RECRUITING, ACTIVE_NOT_RECRUITING, COMPLETED, TERMINATED, WITHDRAWN, SUSPENDED, ENROLLING_BY_INVITATION, UNKNOWN.
`phase`	`any`	optional	Filter by trial phase. One of: EARLY_PHASE1, PHASE1, PHASE2, PHASE3, PHASE4, NA.
`sponsor`	`any`	optional	Filter by sponsor organization. Examples: "Pfizer", "NIH", "Mayo Clinic".
`max_results`	`integer`	optional	Number of results to return (1-50, default 10). (default: 10)

Request Body

{
  "query": "example"
}

get_trial

Get detailed information about a specific clinical trial by NCT ID.

Returns comprehensive trial details including title, summary, status, phase,
conditions, interventions, sponsor, eligibility criteria, outcomes, and locations.

Args:
nct_id: ClinicalTrials.gov NCT identifier (e.g., "NCT03367897", "NCT04368728").
Found in search_trials results or on clinicaltrials.gov.

Returns:
Full trial record with nct_id, brief_title, official_title, brief_summary,
overall_status, phase, study_type, conditions, interventions (name/type/description),
sponsor, collaborators, start_date, completion_date, enrollment,
eligibility_criteria, primary_outcomes, locations.

Parameter	Type	Required	Description
`nct_id`	`string`	required	ClinicalTrials.gov NCT identifier (e.g., "NCT03367897", "NCT04368728"). Found in search_trials results or on clinicaltrials.gov.

Request Body

{
  "nct_id": "example"
}

get_trials_by_condition

Find clinical trials studying a specific condition or disease.

Shortcut for search_trials with condition filter pre-set. Useful for
quickly finding all trials for a disease.

Args:
condition: The condition or disease to search for. Examples: "lung cancer",
"type 2 diabetes", "major depressive disorder", "rheumatoid arthritis".
status: Optional status filter. One of: RECRUITING, NOT_YET_RECRUITING,
ACTIVE_NOT_RECRUITING, COMPLETED, TERMINATED, WITHDRAWN, SUSPENDED,
ENROLLING_BY_INVITATION, UNKNOWN.
max_results: Number of results to return (1-50, default 10).

Returns:
List of trial summaries matching the condition.

Parameter	Type	Required	Description
`condition`	`string`	required	The condition or disease to search for. Examples: "lung cancer", "type 2 diabetes", "major depressive disorder", "rheumatoid arthritis".
`status`	`any`	optional	Optional status filter. One of: RECRUITING, NOT_YET_RECRUITING, ACTIVE_NOT_RECRUITING, COMPLETED, TERMINATED, WITHDRAWN, SUSPENDED, ENROLLING_BY_INVITATION, UNKNOWN.
`max_results`	`integer`	optional	Number of results to return (1-50, default 10). (default: 10)

Request Body

{
  "condition": "example"
}

get_trials_by_sponsor

Find clinical trials run by a specific sponsor organization.

Useful for investigating a company's drug pipeline or an institution's
research portfolio.

Args:
sponsor: Sponsor organization name. Examples: "Pfizer", "Novartis",
"National Cancer Institute", "Mayo Clinic", "Roche".
status: Optional status filter. One of: RECRUITING, NOT_YET_RECRUITING,
ACTIVE_NOT_RECRUITING, COMPLETED, TERMINATED, WITHDRAWN, SUSPENDED,
ENROLLING_BY_INVITATION, UNKNOWN.
max_results: Number of results to return (1-50, default 10).

Returns:
List of trial summaries from the specified sponsor.

Parameter	Type	Required	Description
`sponsor`	`string`	required	Sponsor organization name. Examples: "Pfizer", "Novartis", "National Cancer Institute", "Mayo Clinic", "Roche".
`status`	`any`	optional	Optional status filter. One of: RECRUITING, NOT_YET_RECRUITING, ACTIVE_NOT_RECRUITING, COMPLETED, TERMINATED, WITHDRAWN, SUSPENDED, ENROLLING_BY_INVITATION, UNKNOWN.
`max_results`	`integer`	optional	Number of results to return (1-50, default 10). (default: 10)

Request Body

{
  "sponsor": "123456789"
}

report_feedback

Report a bug, feature request, or general feedback for this data source.

Use this when something doesn't work as expected, when you'd like
a new feature, or when you have suggestions for improvement.

Args:
feedback: Describe the issue or suggestion.
feedback_type: One of 'bug', 'feature_request', or 'general'.

Parameter	Type	Required	Description
`feedback`	`string`	required
`feedback_type`	`string`	optional	(default: "general")

Request Body

{
  "feedback": "example"
}

Quick Start

Shell

curl -X POST "https://context.gnist.ai/rest/clinicaltrials/get_trial" \
  -H "Content-Type: application/json" \
  -H "Gnist-API-Key: YOUR_API_KEY" \
  -d '{"nct_id": "example"}'

Python

import httpx

resp = httpx.post(
    "https://context.gnist.ai/rest/clinicaltrials/get_trial",
    headers={"Gnist-API-Key": "YOUR_API_KEY"},
    json={
  "nct_id": "example"
},
)
print(resp.json())